Abstracts

2019

Altered Hippocampal Epigenetic Regulation Underlying Reduced Cognitive Development in Response to Early Life Environmental Insults

Altered transcriptional regulation underlying alcohol induced liver cirrhosis in a porcine hepatocellular carcinoma model

Development of a Porcine Hepatocellular Carcinoma Model for Targeted Therapeutic Testing

Development of Oncopig Urothelial Carcinoma Cell Lines

Development, Maintenance, and Characterization of Porcine Hepatocellular Carcinoma Cell Lines

Epigenetic Regulation of Combined Hepatocellular-Cholangiocarcinoma Subtypes

Porcine and Human Hepatocellular Carcinoma Cell Lines Present Similar Drug Metabolizing Enzyme Expression Levels and Comparable Sorafenib and Doxorubicin Cytotoxic Responses

2018

Characterization of an inducible alcoholic liver fibrosis model for hepatocellular carcinoma investigation in a transgenic porcine platform

Development and initial application of a porcine-specific MRI and MRE protocol for liver imaging in a large animal cancer model

Development of porcine hepatocellular carcinoma cell lines: Comprehensive in vitro and in vivo characterization

Image-guided catheter-based ultrasound thermal ablation of intramuscular and retroperitoneal sarcomas in the transgenic Oncopig cancer model

Oncopig and human hepatocellular carcinoma cell lines exhibit similar response to liver cancer chemotherapy agents

Oncopig carcinoma cell lines: A foundation for co-clinical trials

2017

Development of a porcine model for pancreatic cancer

Expression of identical genetic mutations across Oncopig cell types results in distinct expression profiles recapitulating transcriptional hallmarks of human tumors

Image-guided catheter-based ultrasound thermal ablation of tumors in genetically engineered oncogenic pigs

Immunological characterization of the Oncopig model and detection of cell-mediated immune responses to cancer

KRASG12D and TP53R167H cooperate to induce pancreatic carcinoma in conditional transgenic Sus scrofa

Major update to the Swine Leukocyte Antigen (SLA) nomenclature system of the International Society for Animal Genetics (ISAG) and the International Union of Immunological Societies (IUIS)

Oncopig Hepatocellular Carcinoma Cell Lines Recapitulate Human Liver Cancer Chemotherapy Responses

Oncopig soft-tissue sarcomas recapitulate key transcriptional features of human sarcomas

Transurethral ultrasound to induce collagen regeneration for treatment of stress urinary incontinence (SUI)

Validation of the oncopig platform as a translational porcine model for human hepatocellular carcinoma

2016

Altered hippocampal DNA methylation, gene transcription, and RNA editing in response to early life environmental insults in two independent studies of cognitive development

Bis(indolyl)methane based retinoid X receptor agonist for efficient nanotherapy in Onco-pigs via In silico-to-In vivo approach

Cancer center designation: Implications for interventional radiologists

Oncopig cancer model: A novel genetically inducible porcine model of hepatocellular carcinoma for interventional radiology locoregional therapy testing

Pigs as a new weapon against cancer: Modeling solid tumors in porcine

Porcine drug metabolism and toxicity in vitro model utilizing transformed hepatocyte cell lines (HepCRE)

The conserved functional role of non-CpG methylation in mammalian and avian brain

The conserved functional role of non-CpG methylation in mammalian and avian brain

The oncopig cancer model as a validated model for human hepatocellular carcinoma

The Swine Leukocyte Antigen (SLA) Nomenclature System of the International Society for Animal Genetics (ISAG) and the International Union of Immunological Societies (IUIS): Update 2016

2015

Swine as an animal model in interventional radiology in the post-genomic era

2014

Adaptive evolution of family Suidae Toll-like receptors (TLRs)

Altered hippocampal DNA methylation and gene expression patterns in an iron deficiency pig model of cognitive development

An inducible large animal cancer model

Characterization of an inducible transgenic p53/Kras oncopig model for cancer

Current status of the swine leukocyte antigen (SLA) system

Effects of oncogene KRAS G12D and p53 R167H expression and genotype on chemotherapy drug resistance in porcine cells

Effects of peripheral viral infection on hippocampal DNA methylation and gene expression patterns in a pig model of cognitive development

The International Swine Methylome Consortium (ISMC): Supporting epigenomics and biomedical research

The International Swine Methylome Consortium (ISMC): Supporting epigenomics and biomedical research

The swine leukocyte antigen (SLA) nomenclature system: 2014 update

Unraveling the swine genome: Implications for human health

2013

454 pyrosequencing reveals a shift in the fecal microbial community composition of genetically identical co-housed pigs fed different diets

A cardiac patch for delivering therapeutic stem cells to the heart following myocardial infarction

An inducible transgenic porcine model for human cancer

An inducible transgenic porcine model for human cancer

Development of an inducible transgenic onco-pig model

Development of an inducible transgenic onco-pig model

In vivo treatment of pig liver using steerable needle therapeutic ultrasound with combined imaging and electromagnetic tracking system

In vivo treatment of spine tumors using needle based therapeutic ultrasound under image guidance with 3D electromagnetic tracking

Sequencing the genomes of the pig and related Suids reveals extensive intra- and inter-specific gene flow during speciation

2012

Cell communication in three-dimensional microenvironments

Porkchops and bacon: My two favorite animals – or how whole genome re-sequencing is revealing mosaic origins and footprints of selection in the pig genome

RNA-seq analyses in pigs: Allelic expression – why make a choice?

The swine leukocyte antigen (SLA) nomenclature system: Current status after 10 years of its establishment

Whole genome re-sequencing of pigs and wild boar reveals unexpected signatures in variation related to biogeography, domestication, and hybridization

2011

A cardiac patch for delivering therapeutic stem cells to the heart following myocardial infarction

A simple and accurate method for accessing gut microbiome composition

A simple, rapid and accurate method for microbiome analysis supporting personalized genomic medicine

A type I monoclonal antibody identifies a common epitope on multiple isoforms of the pig CD34

An inducible transgenic porcine model for the study of human cancer

Analysis of transcriptomes in a porcine tissue collection using RNA-seq and genome assembly 10

Annotation of novel and conserved microRNA genes in the build 10 sus scrofa reference genome and determination of their expression levels in ten different tissues

Detection of porcine imprinted genes through high-throughput cDNA-sequencing (RNA-seq)

Effects of manipulating commensal gut microbiota on porcine innate immunity and TLR methylation

Evolutionary analysis of Betaine Homocysteine Methyltransferase (BHMT) and BHMT-2 genes

Lines and SINES in suids: The repetitive genomic landscape in sus scrofa and related pig species

Modulation of commensal gut and pulmonary microbiomes through oral microbial inoculation and its effects on systemic immune response

Modulation of systemic immune response through commensal gut microbiota

Multiple SNP variations occur in the porcine CD34 gene

Oncopigs as a superior model for breast cancer

Polymorphic patterns in toll-like receptor genes of suid species from different geographic locations

Porcine imprinted genes detected through high-throughput cDNA-sequencing (RNA-seq)

Sequencing multiple genomes of the pig and other suids: Insights in speciation and selection

Shifts in gut microbial community composition associated with degree of solubility of dietary fiber

Single nucleotide polymorphism in toll-like receptor genes in sus species

Strategies to build high-density linkage maps of the porcine 60k SNP chip

2010

A high reslution porcine radiation hybrid map with 10,000 markers

Detecting imprinted genes in the pig genome by high-throughput cDNA-sequencing (RNA-seq)

Genome-wide assessment of genetic diversity in European wild boar

In vitro osteogenic differentiation and in vivo healing capacity of porcine CD34+ adipose-derived stem cells

Independent control of elasticity and drug release rate of an injectable poly(ethyleyene glycol) hydrogel for stem cell mobilization

Insights from whole genome sequence alignment of the domestic (sus scrofa) and javan warty (sus verrucosus) pigs

Manipulation of commensal gut microbiota as a tool to decrease respiratory disease in swine

Sequencing of porcine genes using full-length enriched cDNA libraries: Contribution to annotation of the draft sequence of pig genome

The porcine HapMap project: Genome-wide assessment of nucleotide diversity, haplotype diversity and footprints of selection in the pig

The porcine HapMap projects: Genome-wide analysis of pig, wild boar and suiforme diversity and evolution

When isolation is only apparent: Disentangling the genetic make-up of the Sardinian wild boar by different classes of genetic markers