Peer Reviewed Articles

2019

The Melding of Drug Screening Platforms for Melanoma

TM4SF18 is aberrantly expressed in pancreatic cancer and regulates cell growth

Translating Human Cancer Sequences into Personalized Porcine Cancer Models

2018

BUILDING STRATEGIES FOR PORCINE CANCER MODELS

Characterization of an Inducible Alcoholic Liver Fibrosis Model for Hepatocellular Carcinoma Investigation in a Transgenic Porcine Tumorigenic Platform

Design, Synthesis, and Characterization of Globular Orphan Nuclear Receptor Regulator with Biological Activity in Soft Tissue Sarcoma

Editorial: Building Strategies for Porcine Cancer Models

Genetically induced tumors in the Oncopig model invoke an anti-tumor immune response dominated by cytotoxic CD8β+ T cells and differentiated γδ T cells alongside a regulatory response mediated by FoxP3+ T cells and immuno-regulatory molecules

KRASG12D and TP53R167H Cooperate to Induce Pancreatic Ductal Adenocarcinoma in Sus scrofa Pigs

Of Mice, Dogs, Pigs, and Men: Choosing the Appropriate Model for Immuno-Oncology Research

Translational Animal Models for Liver Cancer

Utilization of Genomics and Functional Genomics to Inform Clinical Decisions in IR

2017

A validated, transitional and translational porcine model of hepatocellular carcinoma

Characteristics and Unmet Clinical Needs Related to Hepatocellular Carcinoma

Gene expression profiling in Pekin duck embryonic breast muscle

Genome-wide SNP data unveils the globalization of domesticated pigs

Oncopig Soft-Tissue Sarcomas Recapitulate Key Transcriptional Features of Human Sarcomas

The Oncopig Cancer Model as a Complementary Tool for Phenotypic Drug Discovery

The Oncopig Cancer Model: An Innovative Large Animal Translational Oncology Platform

2016

3D Printed Stem-Cell-Laden, Microchanneled Hydrogel Patch for the Enhanced Release of Cell-Secreting Factors and Treatment of Myocardial Infarctions

Distinguishing migration events of different timing for wild boar in the Balkans

Emerging technologies to create inducible and genetically defined porcine cancer models

Evidence for adaptation of porcine Toll-like receptors

Evolutionary patterns of Toll-like receptor signaling pathway genes in the Suidae

Evolutionary signals of selection on cognition from the great tit genome and methylome

Gene and transposable element methylation in great tit (Parus major) brain and blood

Genomic diversity and differentiation of a managed island wild boar population

Impact of neonatal iron deficiency on hippocampal DNA methylation and gene transcription in a porcine biomedical model of cognitive development

Peripheral viral infection induced microglial sensome genes and enhanced microglial cell activity in the hippocampus of neonatal piglets

2015

A genetic porcine model of cancer

A hydrogel construct and fibrin-based glue approach to deliver therapeutics in a murine myocardial infarction model

A porcine model system of BRCA1 driven breast cancer

Adaptive evolution of toll-like receptors (TLRs) in the family suidae

Adult porcine genome-wide DNA methylation patterns support pigs as a biomedical model

Evolutionary analyses and natural selection of betaine-homocysteine S-methyltransferase (BHMT) and BHMT2 genes

Individualized medicine and the microbiome in reproductive tract

Tri-modal therapy: Combining hyperthermia with repurposed bexarotene and ultrasound for treating liver cancer

Unraveling the swine genome: Implications for human health

2014

Advances in animal biotechnology

Genetically identical co-housed pigs as models for dietary studies of gut microbiomes

Microfluidic platform for the study of intracellular communication via soluble factor-cell and cell-cell paracrine signaling

2013

Compression-based distance (CBD): A simple, rapid, and accurate method for microbiota composition comparison

Genome sequencing reveals fine scale diversification and reticulation history during speciation in Sus

Leukocyte-mimicking stem cell delivery via in situ coating of cells with a bioactive hyperbranched polyglycerol

Modulation of systemic immune responses through commensal gastrointestinal microbiota

Splicing variants of the porcine betaine-homocysteine S-methyltransferase gene: Implications for mammalian metabolism

2012

A high density recombination map of the pig reveals a correlation between sex-specific recombination and GC content

A highly selective Hsp90 affinity chromatography resin with a cleavable linker

Analyses of pig genomes provide insight into porcine demography and evolution

Association of the porcine transforming growth factor beta type I receptor (TGFBR1) gene with growth and carcass traits

Comprehensive and high-resolution typing of swine leukocyte antigen DQA from genomic DNA and determination of 25 new SLA class II haplotypes

Guiding stem cell fate through microfabricated environments

Large-scale sequencing based on full-length-enriched cDNA libraries in pigs: Contribution to annotation of the pig genome draft sequence

Latexin is down-regulated in hematopoietic malignancies and restoration of expression inhibits lymphoma growth

Livestock marker-assisted selection

Major histocompatibility complex: Biology, functions and roles in disease

Porcine colonization of the Americas: A 60k SNP story

Quantification of the relative roles of niche and neutral processes in structuring gastrointestinal microbiomes

Regions of homozygosity in the porcine genome: Consequence of demography and the recombination landscape

2011

Genome-wide footprints of pig domestication and selection revealed through massive parallel sequencing of pooled DNA

Identification of high utility SNPs for population assignment and traceability purposes in the pig using high-throughput sequencing

Imaging in real-time with FRET the redox response of tumorigenic cells to glutathione perturbation in a microscale flow

Label-free imaging of cell attachment with photonic crystal enhanced microscopy

Molecular characterization and analysis of the porcine betaine homocysteine methyltransferase and betaine homocysteine methyltransferase-2 genes

Neuronal genes for subcutaneous fat thickness in human and pig are identified by local genomic sequencing and combined SNP association study

Pig genomics

Pigs as a model for biomedical sciences

Tuning the non-equilibrium state of a drug-encapsulated super stiff poly (ethylene glycol) hydrogel for stem and progenitor cell mobilization

Ultrasound therapy applicators for controlled thermal modification of tissue

2010

A cloned pig model for examining atherosclerosis induced by high fat, high cholesterol diets

A high-resolution comparative map of porcine chromosome 4 (SSC4)

Age and diet affect gene expression profiles in canine liver tissue

Characterization of porcine pregnane X receptor, farnesoid X receptor and their splice variants

Gene expression profiles of colonic mucosa in healthy young adult and senior dogs

Genomics research: Livestock production

Genomics: Captive breeding and wildlife conservation

Multiple Asian pig origins revealed through genomic analyses

Pig genome sequence: Analysis and publication strategy